Consistent gel cohesivity batch to batch — my midface protocol finally has the predictability it needed.
MS
Dr. M. Santos
Aesthetic physician · Lisbon
High-density cross-linked hyaluronic acid engineered for mid-to-deep dermal injection. Delivers natural-looking volumisation for nose shaping, lip augmentation, chin definition, and jawline contouring. Developed using proprietary MCLPE cross-linking technology for optimal gel cohesivity and predictable clinical performance.
This product is pending regulatory approval in Portugal and Spain. Contact us to be notified when available.
ISO 13485
Sofiderm Deep is a premium biphasic dermal filler formulated with cross-linked hyaluronic acid at a concentration of 20mg/ml. Its high-density gel matrix, created through proprietary MCLPE cross-linking technology, provides exceptional tissue support for mid-to-deep dermal injection applications.
MCLPE cross-linked HA at 20 ± 3 mg/ml creates a cohesive gel matrix that integrates smoothly with surrounding tissue. The high molecular weight and dense cross-linking provide structural support while maintaining a natural feel and movement. The gel's rheological properties ensure even distribution and predictable lift.
| Product | Sofiderm Deep |
| Volume | 2ml pre-filled syringe |
| HA Concentration | 20 ± 3 mg/ml |
| Cross-linking | MCLPE Technology (BDDE) |
| Needle | 27G TW |
| Application | Mid-to-deep dermis |
| Indications | Nose, lips, chin, jawline, deep wrinkles |
| Duration | 12–18 months |
| Storage | 2–25°C, protect from light |
| Shelf Life | 24 months |
| Certification | ISO 9001:2015 · ISO 13485 · GDPR |
| Manufacturer | Hangzhou Techderm |
The proprietary Multi-phase Cross-Linked Polymer Encapsulation (MCLPE) process produces a homogeneous gel matrix with controlled particle size distribution. This results in a filler with optimal viscoelastic properties: high G' (elastic modulus) for effective lift and projection, balanced with sufficient viscosity for smooth injection through fine-gauge needles.
Clinical evaluations demonstrate consistent volumisation across treatment areas, with a favourable safety profile and high patient satisfaction ratings. The cross-linking density is calibrated to resist enzymatic degradation while maintaining biocompatibility, contributing to the 12–18 month duration of effect observed in post-market surveillance data.
All Sofiderm products are manufactured under ISO 13485 quality management systems and comply with EU Medical Device Regulation requirements for CE marking.
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