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Cross-linked HA dermal fillers for facial correction and volumisation. All formulations at 20 ± 3 mg/ml via MCLPE technology.
View Dermal FillersManufacturing Partner
by Hangzhou Techderm Biological Products Co., Ltd
Sofiderm
Hangzhou, China
The clinical-grade hyaluronic acid line behind ORVIDA’s professional catalogue. CE-certified, ISO-compliant, and MDSAP-audited. Exclusively available to licensed clinics across Portugal and Spain.
2015
Founded
CE 2460
Notified Body
MCLPE™
Proprietary Technology
About the Manufacturer
Advancing Aesthetic Science from Hangzhou
Hangzhou Techderm Biological Products Co., Ltd is a medical-grade manufacturer of hyaluronic acid aesthetic products. The company’s research programme is anchored in MCLPE — a proprietary cross-linking process that achieves exceptional gel consistency, longevity, and clinical safety across the Sofiderm product range.
Sofiderm covers the full spectrum of clinical indications — from superficial fine line correction to deep volumisation and high-volume body contouring. ORVIDA holds exclusive distribution rights for Portugal and Spain.
Key Facts
ManufacturerHangzhou Techderm
LocationHangzhou, China
BrandSofiderm
HA Concentration20 ± 3 mg/ml
Cross-linkingMCLPE™ (BDDE)
Notified BodyCE 2460
MCLPE Technology
Precision Cross-Linking at the Molecular Level
MCLPE — Multi-Chain Layered Process Engineering — is Techderm’s proprietary cross-linking methodology. Applied at the molecular level, MCLPE produces a more uniform polymer matrix than conventional BDDE processes. The result: predictable rheological properties, reduced degradation variability, and consistent clinical performance across every syringe.
Explore the ScienceFree HA Chains
Natural hyaluronic acid strands in aqueous solution.
MCLPE Cross-Linking
Layered compression process applies BDDE bridges at controlled depth.
Stable Gel Matrix
Uniform polymer network with precise G’ modulus and longevity.
AMWC Monaco 2026
Best Injectable Body Filler
Sofiderm Derm Sub-Skin 20ml was awarded Best Injectable Body Filler at the Aesthetic & Anti-Aging Medicine World Congress, held in Monte Carlo, March 2026. The award recognises outstanding clinical performance in high-volume body contouring applications.
View Derm Sub-Skin
Quality & Compliance
Regulatory Certifications
CE 2460
Class III medical device. EU MDR compliant.
ISO 13485
Quality management system for medical devices.
ISO 9001
General quality management certification.
MDSAP
Multi-jurisdictional single audit program.
Product Range
Three Categories. Every Aesthetic Indication.
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Non-crosslinked mesotherapy solutions for skin hydration, biorevitalisation, and hair restoration.
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Active ingredient complexes for targeted aesthetic outcomes. 10 × 5ml vials per treatment unit.
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Official Distribution
Order Sofiderm Products
Exclusively Distributed by ORVIDA
ORVIDA holds exclusive distribution rights for Sofiderm products across Portugal and Spain. Order through your ORVIDA professional account. All orders ship with full regulatory documentation.