Consistent gel cohesivity batch to batch — my midface protocol finally has the predictability it needed.
MS
Dr. M. Santos
Aesthetic physician · Lisbon
High-density cross-linked hyaluronic acid engineered for mid-to-deep dermal injection. Delivers natural-looking volumisation for nose shaping, lip augmentation, chin definition, and jawline contouring. Developed using proprietary MCLPE cross-linking technology for optimal gel cohesivity and predictable clinical performance.
ISO 13485
Sofiderm Deep is a premium biphasic dermal filler formulated with cross-linked hyaluronic acid at a concentration of 20mg/ml. Its high-density gel matrix, created through proprietary MCLPE cross-linking technology, provides exceptional tissue support for mid-to-deep dermal injection applications.
MCLPE cross-linked HA at 20 ± 3 mg/ml creates a cohesive gel matrix that integrates smoothly with surrounding tissue. The high molecular weight and dense cross-linking provide structural support while maintaining a natural feel and movement. The gel's rheological properties ensure even distribution and predictable lift.
| Product | Sofiderm Deep |
| Volume | 2ml pre-filled syringe |
| HA Concentration | 20 ± 3 mg/ml |
| Cross-linking | MCLPE Technology (BDDE) |
| Needle | 27G TW |
| Application | Mid-to-deep dermis |
| Indications | Nose, lips, chin, jawline, deep wrinkles |
| Duration | 12–18 months |
| Storage | 2–25°C, protect from light |
| Shelf Life | 24 months |
| Certification | ISO 9001:2015 · ISO 13485 · GDPR |
| Manufacturer | Hangzhou Techderm |
The proprietary Multi-phase Cross-Linked Polymer Encapsulation (MCLPE) process produces a homogeneous gel matrix with controlled particle size distribution. This results in a filler with optimal viscoelastic properties: high G' (elastic modulus) for effective lift and projection, balanced with sufficient viscosity for smooth injection through fine-gauge needles.
Clinical evaluations demonstrate consistent volumisation across treatment areas, with a favourable safety profile and high patient satisfaction ratings. The cross-linking density is calibrated to resist enzymatic degradation while maintaining biocompatibility, contributing to the 12–18 month duration of effect observed in post-market surveillance data.
All Sofiderm products are manufactured under ISO 13485 quality management systems and comply with EU Medical Device Regulation requirements for CE marking.
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